HORDB

ID: hor006452
Uniprot ID: P91797
Protein name: Molluscan insulin-related peptide 7 B chain
Gene name: NA
Organism: Lymnaea stagnalis (Great pond snail) (Helix stagnalis)
Family: Insulin family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Lymnaea (genus), Lymnaeidae (family), Lymnaeoidea (superfamily), Hygrophila , Panpulmonata , Euthyneura , Heterobranchia (subclass), Gastropoda (class), Mollusca (phylum), Lophotrochozoa , Spiralia , Protostomia , Bilateria , Eumetazoa , Metazoa (kingdom), Opisthokonta , Eukaryota (superkingdom),cellular organisms
GO MF: GO:0005179 hormone activity
GO BP: GO:0007165 signal transduction
GO CC: GO:0005576 extracellular region; GO:0030133 transport vesicle; GO:0031410 cytoplasmic vesicle

Sequence: QQVNTCTMFSRQHPRGLCGNRLARAHANLCFLLRNTYPDIFP
Length: 42(26-67)
Propeptide: MNASVESCLTFTFVLVALCVGLTIGQQVNTCTMFSRQHPRGLCGNRLARAHANLCFLLRNTYPDIFPRKRSVDNTFEKVYSIPLSVLAELDLSDDDWGAYVSKKDIPYRSETNGLSGANFESSAFDKQLELPAMKSTTSQLFRILKLRGSRLKREVMAEPSLVCDCCYNECSVRKLATYC
Signal peptide: MNASVESCLTFTFVLVALCVGLTIG
Modification: T1 Pyrrolidone carboxylic acid
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor006452_AF2.pdb

hor006452_ESM.pdb

Mass:	559312	Formula:	C211H332N68O57S4
Absent amino acids:	EKW	Common amino acids:	LR
pI:	9.66	Basic residues:	7
Polar residues:	14	Hydrophobic residues:	13
Hydrophobicity:	-37.62	Boman Index:	-9107
Half-Life:	0.8 hour	Half-Life Yeast:	10 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	69.76
Instability Index:	3015	Extinction Coefficient cystines:	1615
Absorbance 280nm:	39.39

PubMed ID: 8848162
Title: Expression and characterization of molluscan insulin-related peptide VII from the mollusc Lymnaea stagnalis.